Cesare Gennari Selected Research

Peptidomimetics

6/2020	Multimeric Presentation of RGD Peptidomimetics Enhances Integrin Binding and Tumor Cell Uptake.
2/2019	Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate.
1/2018	Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.
1/2016	αvβ3 Integrin-Targeted Peptide/Peptidomimetic-Drug Conjugates: In-Depth Analysis of the Linker Technology.
6/2013	Determination of the binding epitope of RGD-peptidomimetics to αvβ3 and α(IIb)β3 integrin-rich intact cells by NMR and computational studies.
12/2012	Synthesis and biological evaluation (in vitro and in vivo) of cyclic arginine-glycine-aspartate (RGD) peptidomimetic-paclitaxel conjugates targeting integrin αVβ3.
5/2012	Cyclic RGD peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.

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Cesare Gennari Research Topics

Disease

12	Neoplasms (Cancer) 05/2022 - 08/2009
5	Glioblastoma (Glioblastoma Multiforme) 10/2019 - 04/2015
2	Melanoma (Melanoma, Malignant) 06/2019 - 01/2019
2	Carcinoma (Carcinomatosis) 01/2018 - 12/2012
1	Ovarian Neoplasms (Ovarian Cancer) 05/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 05/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 02/2019
1	Adenocarcinoma 01/2018
1	Breast Neoplasms (Breast Cancer) 02/2017
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2015
1	Urinary Bladder Neoplasms (Bladder Cancer) 06/2013
1	Acquired Immunodeficiency Syndrome (AIDS) 12/2005

Drug/Important Bio-Agent (IBA)

15	IntegrinsIBA 06/2020 - 05/2012
7	PeptidomimeticsIBA 06/2020 - 05/2012
7	LigandsIBA 06/2020 - 12/2012
6	Pharmaceutical PreparationsIBA 05/2022 - 12/2012
3	Paclitaxel (Taxol)FDA LinkGeneric 05/2022 - 12/2012
3	Biological ProductsIBA 10/2019 - 04/2015
2	arginyl-glycyl-aspartic acidIBA 06/2020 - 01/2016
2	Peptides (Polypeptides)IBA 06/2020 - 01/2016
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 05/2022
1	serum P-component (CIt)IBA 05/2022
1	4-azidobenzylcarazolol (pABC)IBA 05/2022
1	gonadotropin-releasing hormone-IIIIBA 05/2022
1	Cathepsin BIBA 05/2022
1	Daunorubicin (Cerubidine)FDA LinkGeneric 05/2022
1	DipeptidesIBA 05/2022
1	LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA 05/2022
1	EnzymesIBA 02/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	GlucuronidaseIBA 01/2019
1	Vascular Endothelial Growth FactorsIBA 01/2019
1	AmanitinsIBA 01/2018
1	SuspensionsIBA 02/2017
1	AntigensIBA 01/2016
1	AntibodiesIBA 01/2016
1	EpitopesIBA 06/2013
1	VitronectinIBA 05/2012
1	chaetominineIBA 08/2009
1	Ether (Diethyl Ether)IBA 12/2005
1	allyl alcohol (allylic alcohol)IBA 12/2005

Therapy/Procedure

4	Therapeutics 05/2022 - 01/2016
1	Drug Therapy (Chemotherapy) 01/2016